At Men’s Vitality Center in Glendale, testosterone replacement therapy is one of our most popular health services. Low testosterone levels can be incredibly frustrating to experience, with such symptoms as fatigue, low sex drive, problems concentrating, lowered self-esteem, and decreased muscle mass. Fortunately, testosterone replacement therapy is accessible, simple, and relatively painless. However, this was not always an option for men experiencing these symptoms.

In a sense, research into testosterone replacement therapy has actually been around for centuries. In the 1800s, Arnold Adolph Berthold, a German scientist, was the first person to formally study how hormones and behavior are linked through his experiments on roosters, and is therefore considered a pioneer of endocrinology. In his experiments, he castrated roosters and found that without their testes, their behavior changed; they were no longer able to mate, were less aggressive, and no longer crowed in the morning. This demonstrated for the first time that organs besides the brain have control over behavior. Later, French scientist Charles-Edouard Brown-Séquard used this discovery to conduct experiments on himself to see what effect injecting himself with animal testicular fluids would have. He discovered that he felt stronger and healthier, and so began more research into how they might use these discoveries to help men. In 1935, testosterone was synthesized for the first time, paving the way for testosterone replacement therapy. Initially, testosterone was almost exclusively implanted, as oral consumption caused liver toxicity. By the 1950s, testosterone injections became the most prevalent method. In the 1970s, an effective and safe pill came onto the market, and today there are topical ointments and patches as well; however, injections remain the most effective choice.

If you are concerned that you may have low testosterone levels, contact Men’s Vitality Clinic in Glendale, AZ to learn more about testosterone replacement therapy.